Targeting Vascular Risk Factors to Reduce Dementia Incidence in Old Age: Extended Follow-up of the Prevention of Dementia by Intensive Vascular Care (preDIVA) Randomized Clinical Trial

Marieke P Hoevenaar-Blom; Edo Richard; Eric P Moll van Charante; Lennard L van Wanrooij; Wim B Busschers; Jan W van Dalen; Wim A van Gool

doi:10.1001/jamaneurol.2021.3542

Targeting Vascular Risk Factors to Reduce Dementia Incidence in Old Age: Extended Follow-up of the Prevention of Dementia by Intensive Vascular Care (preDIVA) Randomized Clinical Trial

JAMA Neurol. 2021 Dec 1;78(12):1527-1528. doi: 10.1001/jamaneurol.2021.3542.

Authors

Marieke P Hoevenaar-Blom^{1

2

3}, Edo Richard^{1

3}, Eric P Moll van Charante^{1

4}, Lennard L van Wanrooij², Wim B Busschers⁴, Jan W van Dalen^{1

2

3}, Wim A van Gool¹

Affiliations

¹ Department of Public and Occupational Health, Amsterdam UMC, University of Amsterdam, Amersterdam, the Netherlands.
² Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
³ Department of Neurology, Donders Institute for Brain, Behaviour and Cognition, Radboud University Medical Centre, Nijmegen, the Netherlands.
⁴ Department of General Practice, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

Abstract

This follow-up analysis of a randomized clinical trial investigates the association of multidomain interventions targeting vascular risk factors with dementia incidence among community-dwelling older adults.

Publication types

Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aging*
Cardiovascular Diseases / prevention & control
Dementia / epidemiology
Dementia / prevention & control*
Female
Follow-Up Studies
Healthy Lifestyle*
Humans
Incidence
Male
Risk Factors