SEOR SBRT-SG stereotactic body radiation therapy consensus guidelines for non-spine bone metastasis

Clin Transl Oncol. 2022 Feb;24(2):215-226. doi: 10.1007/s12094-021-02695-6. Epub 2021 Oct 11.


The use of stereotactic body radiation therapy (SBRT) to treat non-spine bone metastases (NSBM) is becoming increasingly common in clinical practice. The clinical advantages of SBRT include good pain control and high local control rates, although only limited data are available. The Spanish Society of Radiation Oncology (SEOR) SBRT group recently convened a task force of experts in the field to address key questions related to SBRT for NSBM, including treatment indications, planning, techniques, and dose fractionation. The task force reviewed the available literature to develop evidence-based recommendations for the safe application of NSBM SBRT and to standardize and optimize SBRT processes. The present document provides a comprehensive analysis of the available data, including ongoing clinical trials and controversies, providing clinically applicable recommendations.

Keywords: Consensus guidelines: non spinal bone metastases; Non-spine bone metastases; Stereotactic body radiation therapy (SBRT).

Publication types

  • Consensus Development Conference
  • Practice Guideline

MeSH terms

  • Bone Neoplasms / radiotherapy*
  • Bone Neoplasms / secondary*
  • Humans