All eyes on a phosphatase in glioma stem cells

J Exp Med. 2021 Nov 1;218(11):e20211605. doi: 10.1084/jem.20211605. Epub 2021 Oct 12.


In this issue of JEM, Zhang et al. (2021. J. Exp. Med. identify a dependency of glioma stem cells on tyrosine phosphatase activity of EYA2 and a new role for this phosphatase at the centrosome, offering a new therapeutic approach to target mitotic activity.

Publication types

  • Comment

MeSH terms

  • Glioma* / genetics
  • Humans
  • Neoplastic Stem Cells
  • Phosphoric Monoester Hydrolases*


  • Phosphoric Monoester Hydrolases