Were magnetic materials useful in cancer therapy?

Biomed Pharmacother. 2021 Dec:144:112321. doi: 10.1016/j.biopha.2021.112321. Epub 2021 Oct 15.

Abstract

Cancer is one of the major challenges fronting the biomedical basic researches in our time. The study and development of effective therapeutic strategies for cancer therapy are vital. Among the many probable core constituents of nanoparticles, magnetite-based nanoparticles have been widely studied for cancer therapy owing to their inherent magnetic features, multifunctional design, biodegradable and biocompatible properties. Magnetic nanoparticles have been also designed for utilizing as contrast enhancer agents for magnetic resonance imaging, drug delivery systems, and most recently as a therapeutic element in inducing cellular death in tumor ablation therapies. This review aimed to provide an overview of the various applications of magnetic nanoparticles and recent achievements in developing these advanced materials for cancer therapy.

Keywords: Advanced materials; Cancer; Magnetic nanoparticles; Therapeutic strategies.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / administration & dosage*
  • Antineoplastic Agents / adverse effects
  • Contrast Media* / adverse effects
  • Drug Carriers* / adverse effects
  • Humans
  • Magnetic Field Therapy* / adverse effects
  • Magnetic Iron Oxide Nanoparticles* / adverse effects
  • Molecular Imaging*
  • Nanomedicine*
  • Neoplasms / diagnostic imaging*
  • Neoplasms / therapy*

Substances

  • Antineoplastic Agents
  • Contrast Media
  • Drug Carriers