Micronodular basal cell carcinoma of the scrotum: a case report and review of the literature

J Med Case Rep. 2021 Oct 17;15(1):512. doi: 10.1186/s13256-021-03124-6.


Introduction: Basal cell carcinoma is the most common nonmelanotic skin cancer. It has variable clinical and histological subtypes that vary in their aggressiveness and liability to recurrence and metastasis. Chronic ultraviolet radiation exposure is considered to be the main risk factor for developing basal cell carcinoma; therefore, it typically arises on sun-exposed skin, mainly the head and neck.

Case presentation: We present the case of a 55-year-old Caucasian male who presented with a lesion on the scrotum for 2 years. The lesion was clinically presumed benign and initially treated with curettage. Microscopic examination revealed an incompletely resected micronodular basal cell carcinoma with sebaceous differentiation. Therefore, a second excisional biopsy was performed to completely excise the incidentally discovered malignant tumor.

Conclusion: We report the first case of micronodular basal cell carcinoma arising on the scrotum. The goal of our article is to draw clinicians' attention to the possible involvement of unexposed skin with basal cell carcinoma, and we highlight the importance of accurate diagnosis and prompt treatment due to the aggressive nature of micronodular basal cell carcinoma.

Keywords: Basal cell carcinoma; Case report; Micronodular; Scrotum.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Carcinoma, Basal Cell* / diagnostic imaging
  • Carcinoma, Basal Cell* / surgery
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Scrotum / diagnostic imaging
  • Scrotum / surgery
  • Skin Neoplasms* / surgery
  • Ultraviolet Rays