Synthesis and characterization of chitosan-PEG-Ag nanocomposites for antimicrobial application

K S V Krishna Rao; P Ramasubba Reddy; Yong-Ill Lee; Changdae Kim

doi:10.1016/j.carbpol.2011.07.028

Synthesis and characterization of chitosan-PEG-Ag nanocomposites for antimicrobial application

Carbohydr Polym. 2012 Jan 4;87(1):920-925. doi: 10.1016/j.carbpol.2011.07.028. Epub 2011 Jul 28.

Authors

K S V Krishna Rao¹, P Ramasubba Reddy², Yong-Ill Lee³, Changdae Kim⁴

Affiliations

¹ Department of Chemistry, Yogi Vemana University, Kadapa 516 003, India; Department of Chemistry, Changwon National University, Changwon, South Korea. Electronic address: drksvkrishna@yahoo.com.
² Department of Chemistry, Yogi Vemana University, Kadapa 516 003, India.
³ Department of Chemistry, Changwon National University, Changwon, South Korea. Electronic address: yilee@cwnu.ac.kr.
⁴ Department of Physics, Mokpo National University, Mokpo 534-729, South Korea.

PMID: 34663055
DOI: 10.1016/j.carbpol.2011.07.028

Abstract

New chitosan nanocomposites doped with silver nanoparticles were synthesized by a simple method. The chitosan particles were prepared by desolvation followed by crosslinking with poly(ethylene glycol-di-aldehyde), this was prepared with poly(ethylene glycol) in the presence of a silver nitrate solution. The developed nanocomposites were characterized using UV-visible, FTIR, XRD, TGA, SEM and TEM to understand their physico-chemical properties. These nanocomposites were shown to have anti bacterial activity towards Escherichia coli.

Keywords: Antimicrobial activity; Chitosan; Nanocomposite; Poly(ethylene glycol).