Projection-based dynamic tomography

Phys Med Biol. 2021 Nov 3;66(21). doi: 10.1088/1361-6560/ac309e.

Abstract

Objective. This paper proposes a 4D dynamic tomography framework that allows a moving sample to be imaged in a tomograph as well as the associated space-time kinematics to be measured with nothing more than a single conventional x-ray scan.Approach. The method exploits the consistency of the projection/reconstruction operations through a multi-scale procedure. The procedure is composed of two main parts solved alternatively: a motion-compensated reconstruction algorithm and a projection-based measurement procedure that estimates the displacement field directly on each projection.Main results. The method is applied to two studies: a numerical simulation of breathing from chest computed tomography (4D-CT) and a clinical cone-beam CT of a breathing patient acquired for image guidance of radiotherapy. The reconstructed volume, initially blurred by the motion, is cleaned from motion artifacts.Significance. Applying the proposed approach results in an improved reconstruction quality showing sharper edges and finer details.

Keywords: breathing motion; computed tomography; motion compensation; tomographic reconstruction.

MeSH terms

  • Algorithms
  • Artifacts
  • Cone-Beam Computed Tomography* / methods
  • Four-Dimensional Computed Tomography* / methods
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Motion
  • Phantoms, Imaging