Transcatheter device closure of perimembranous ventricular septal defect associated with indirect Gerbode defect: A retrospective study

Ann Pediatr Cardiol. 2021 Jul-Sep;14(3):397-400. doi: 10.4103/apc.APC_143_20. Epub 2021 Aug 26.

Abstract

Perimembranous ventricular septal defect (pmVSD) is a common congenital heart disease that is sometimes associated with indirect left ventricle (LV) to right atrium (RA) shunt (indirect Gerbode defect). This defect has a rare chance of spontaneous closure and therefore was usually closed surgically in the past, but more recently transcatheter closure has been reported by a few authors. In our study, we have described a series of 14 children (age ranging from 1.2 to 12 years and weight ranging from 7.2 to 25.5 kg) with the above-mentioned defect which were closed by various interventional devices. The procedures were successful in complete elimination of pmVSD and immediate reduction of indirect LV-RA shunts with negligible residual tricuspid regurgitation on follow-up. In our midterm experience, the judicious use of double-disc devices is efficacious for occluding pmVSD associated with indirect Gerbode defect.

Keywords: Amplatzer duct occluder II device; gerbode defect; percutaneous device closure; perimembranous ventricular septal defect.