Sudden death due to amyloidosis of intramural coronaries in a patient with amyloidosis of hip joint - An autopsy report with a review of literature

Indian J Pathol Microbiol. 2021 Oct-Dec;64(4):791-794. doi: 10.4103/ijpm.ijpm_1486_20.

Abstract

Amyloidosis is caused by an extracellular accumulation of insoluble fibrillary protein predominantly in the kidneys, spleen, and heart. The deposition of amyloid into the joints, synovia, and osseous tissues (amyloid arthropathy) is an uncommon condition with only a few case reports in the English literature. Similarly, amyloid deposition predominantly limited to the vascular wall is rarely described. In this report, we describe an additional case of amyloidosis of the hip joint along with amyloidosis of intramural coronaries leading to sudden death in a middle-aged male.

Keywords: Amyloidosis; arthropathy; heart; sudden death.

Publication types

  • Case Reports

MeSH terms

  • Amyloid / metabolism
  • Amyloidosis / mortality*
  • Amyloidosis / pathology*
  • Coronary Vessels / pathology
  • Death, Sudden, Cardiac / pathology*
  • Hip Joint / diagnostic imaging
  • Hip Joint / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged

Substances

  • Amyloid