Eosinophils, beyond IL-5

Stephane Esnault; Mats W Johansson; Sameer K Mathur

doi:10.3390/cells10102615

Eosinophils, beyond IL-5

Cells. 2021 Oct 1;10(10):2615. doi: 10.3390/cells10102615.

Authors

Stephane Esnault¹, Mats W Johansson^{1

2

3}, Sameer K Mathur¹

Affiliations

¹ Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA.
² Metabolism Theme, Morgridge Institute for Research, Madison, WI 53706, USA.
³ Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53706, USA.

Abstract

New therapeutic monoclonal antibodies targeting the IL-5/IL-5 receptor pathway are extremely efficient in depleting blood eosinophils from subjects with asthma [...].

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Asthmatic Agents / therapeutic use
Antibodies, Monoclonal, Humanized / therapeutic use
Asthma / drug therapy*
Eosinophils / cytology
Eosinophils / immunology*
Humans
Interleukin-5 / immunology*

Substances

Anti-Asthmatic Agents
Antibodies, Monoclonal, Humanized
IL5 protein, human
Interleukin-5