Gruber-Frantz tumor: a rare pancreatic neoplasm

Rev Esp Enferm Dig. 2021 Oct 25. doi: 10.17235/reed.2021.8345/2021. Online ahead of print.

Abstract

We present the case of a 37-year-old woman with abdominal pain in the epigastrium radiating to the right flank for a month of evolution. On physical examination, epigastric mass is palpated, firm and painless. Computed tomography (CT) showed a cystic tumor in the body and tail of the pancreas with solid areas and defined borders (12x10 cm), which displaces structures. Endoscopic ultrasound (EUS)-guided fine needle biopsy was taken, with consistent cytology of SPT. Subsequently, a distal pancreatectomy with tumor resection and nodal dissection was performed. Cytology reported discohesive cells, some arranged around capillaries, with small nuclei with clefts, CK7 negative and β-catenin positive. After 4 years of follow-up, there is no evidence of recurrence.