Diversity and convergence within peripheral glia development

Trends Neurosci. 2021 Dec;44(12):930-932. doi: 10.1016/j.tins.2021.10.004. Epub 2021 Oct 21.

Abstract

In a recent study, Tasdemir-Yilmaz and colleagues used single-cell RNA sequencing to reveal how diversity among peripheral glia changes with development and also identified unifying genetic profiles that are shared between mature glia. These data highlight new tools and pathways in which to understand peripheral glial development and function.

Keywords: Schwann cells; development; glial heterogeneity; myelin; satellite glia.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Humans
  • Neurogenesis
  • Neuroglia* / metabolism
  • Schwann Cells* / metabolism