Idiopathic desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy: A case report

Hiroshi Ishimoto; Noriho Sakamoto; Mutsumi Ozasa; Shin Tsutsui; Atsuko Hara; Takashi Kido; Hiroyuki Yamaguchi; Kazuko Yamamoto; Yasushi Obase; Yuji Ishimatsu; Hiroshi Mukae

doi:10.1016/j.rmcr.2021.101523

Idiopathic desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy: A case report

Respir Med Case Rep. 2021 Oct 6:34:101523. doi: 10.1016/j.rmcr.2021.101523. eCollection 2021.

Authors

Affiliations

¹ Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
² Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
³ Department of Radiology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
⁴ Department of Nursing, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8520, Japan.

Abstract

A 60-year-old Japanese man with a history of heavy smoking came to our hospital for a detailed examination, suspecting interstitial pneumonia because of gradually increasing dyspnea on exertion over a period of one year. Chest high-resolution computed tomography revealed ground-glass shadows with emphysematous changes. Pathological analysis of samples obtained using transbronchial lung cryobiopsy revealed an accumulation of alveolar macrophages with abundant eosinophilic cytoplasm in the alveolar space. Following a multidisciplinary discussion, the patient was diagnosed with desquamative interstitial pneumonia. To our knowledge, this is the first detailed report of desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy.

Keywords: Desquamative interstitial pneumonia; Multidisciplinary discussion; Transbronchial lung cryobiopsy.

Publication types

Case Reports