Immunosuppressant Management in Renal Transplant Patients with COVID-19

Biomed Res Int. 2021 Oct 14:2021:9318725. doi: 10.1155/2021/9318725. eCollection 2021.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic poses a special risk for both immunosuppressed patients, especially transplant recipients. Although the knowledge about this infection is growing, many uncertainties remain, particularly regarding the kidney. Kidney transplant recipients (KDRs) should be considered immunocompromised hosts since a potential risk for infection, comorbidity, and immunosuppression exposure exists. Additionally, the management of immunosuppressive agents in KDRs remains challenging. Potential drug interactions with immunosuppressive treatment escalated the risk of unwanted side effects. In this review, we aimed to attain an augmented awareness and improved management immunosuppressant for COVID-19 KDRs.

Publication types

  • Review

MeSH terms

  • COVID-19 / immunology*
  • Humans
  • Immunocompromised Host
  • Immunosuppressive Agents / immunology
  • Immunosuppressive Agents / pharmacokinetics
  • Immunosuppressive Agents / therapeutic use*
  • Kidney Transplantation* / adverse effects
  • Kidney Transplantation* / mortality
  • SARS-CoV-2 / drug effects

Substances

  • Immunosuppressive Agents