Serpiginous Choroiditis Complicated with Choroidal Neovascular Membrane Detected using Optical Coherence Tomography Angiography: A Case Series and Literature Review

Turk J Ophthalmol. 2021 Oct 26;51(5):326-333. doi: 10.4274/tjo.galenos.2021.49323.


Serpiginous choroiditis (SC) is a rare, chronic, recurrent, progressive disease of unknown origin. The inflammatory process of SC can disrupt Bruch's membrane, allowing occasional choroidal vascular growth, leading to significant visual loss even in the healed stages of the disease. Optical coherence tomography angiography (OCTA) can help in the detection of choroidal neovascular membrane (CNV), leading to a definitive diagnosis and thereby guide the initiation of intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment. We report herein two cases of SC complicated with a CNV detected with OCTA and treated with a series of anti-VEGF injections.

Keywords: Serpiginous choroiditis; anti-VEGF; neovascular membrane; optical coherence tomography angiography.

Publication types

  • Review

MeSH terms

  • Choroidal Neovascularization* / diagnosis
  • Choroidal Neovascularization* / drug therapy
  • Choroidal Neovascularization* / etiology
  • Choroiditis* / complications
  • Choroiditis* / diagnosis
  • Choroiditis* / drug therapy
  • Fluorescein Angiography
  • Humans
  • Tomography, Optical Coherence
  • Visual Acuity
  • White Dot Syndromes*