Long sleep duration is associated with cognitive frailty among older community-dwelling adults: results from West China Health and Aging Trend study

Yunli Zhao; Ying Lu; Wanyu Zhao; Yanyan Wang; Meiling Ge; Lixing Zhou; Jirong Yue; Birong Dong; Qiukui Hao

doi:10.1186/s12877-021-02455-9

Long sleep duration is associated with cognitive frailty among older community-dwelling adults: results from West China Health and Aging Trend study

BMC Geriatr. 2021 Oct 27;21(1):608. doi: 10.1186/s12877-021-02455-9.

Authors

Yunli Zhao^{1

2}, Ying Lu³, Wanyu Zhao^{1

2}, Yanyan Wang^{1

2}, Meiling Ge^{1

2}, Lixing Zhou^{1

2}, Jirong Yue^{1

2}, Birong Dong^{4

5}, Qiukui Hao^{1

2}

Affiliations

¹ National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.37 Guo Xue Xiang, Chengdu, China.
² Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, No.37 GuoXueXiang, Chengdu, 610041, Sichuan, China.
³ National Clinical Research Center for Geriatrics and Department of General Practice, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, Chengdu, China.
⁴ National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.37 Guo Xue Xiang, Chengdu, China. Birongdong123@outlook.com.
⁵ Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, No.37 GuoXueXiang, Chengdu, 610041, Sichuan, China. Birongdong123@outlook.com.

Abstract

Objective: To investigate the association between sleep duration and cognitive frailty among older adults dwelling in western China.

Methods: We used the baseline data from West China Health and Aging Trend (WCHAT) study. Sleep duration was classified as short sleep duration (< 6 h), normal sleep duration (6-8 h) and long sleep duration (≥ 9 h). Fried frailty criteria and Short Portable Mental Status Questionnaire were used to measure cognitive frailty. Multinomial logistic regression was conducted to estimate odds ratio (OR) and 95% confidence interval (CI).

Results: A total of 4093 older adults (age = 67.8 ± 5.9 years, 1708 males and 2385 females) were included in the analysis. The prevalence of cognitive frailty was 11.8% among older adults in western China. Approximately 11.9% participants had short sleep duration (< 6 h); 22.2% had a long sleep duration (≥ 9 h). After adjusting for covariates, only long sleep duration was significantly associated with high risk of cognitive frailty (OR = 2.07, 95%CI = 1.60-2.68, P < 0.001) in western China older adults compared to normal sleep duration.

Conclusions: Long sleep duration was significantly related to cognitive frailty in older adults. Intervention for long sleep duration may be helpful to prevent cognitive frailty.

Trial registration: Chinese Clinical Trial Registry: ChiCTR1800018895 .

Keywords: Cognitive frailty; Older adults; Sleep duration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aging
China / epidemiology
Cognition
Cross-Sectional Studies
Female
Frail Elderly
Frailty* / diagnosis
Frailty* / epidemiology
Geriatric Assessment
Humans
Independent Living
Male
Sleep