Task-based and Resting State Functional MRI in Children

Mohit Maheshwari; Tejaswini Deshmukh; Eric C Leuthardt; Joshua S Shimony

doi:10.1016/j.mric.2021.06.005

Task-based and Resting State Functional MRI in Children

Magn Reson Imaging Clin N Am. 2021 Nov;29(4):527-541. doi: 10.1016/j.mric.2021.06.005.

Authors

Mohit Maheshwari¹, Tejaswini Deshmukh², Eric C Leuthardt³, Joshua S Shimony⁴

Affiliations

¹ Department of Radiology, Medical College of Wisconsin, Children's Wisconsin, MS - 721, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: mmahesh@mcw.edu.
² Department of Radiology, Medical College of Wisconsin, Children's Wisconsin, MS - 721, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA.
³ Department of Neurosurgery, Washington University, 4525 Scott Avenue Campus Box 8131, St Louis, MO 63141, USA.
⁴ Mallinckrodt Institute of Radiology, Washington University, 4525 Scott Avenue Campus Box 8131, St Louis, MO 63141, USA.

PMID: 34717843
DOI: 10.1016/j.mric.2021.06.005

Abstract

Functional MR imaging (MRI) is a valuable tool for presurgical planning and is well established in adult patients. The use of task-based fMRI is increasing in pediatric populations because it provides similar benefits for pre-surgical planning in children. This article reviews special adaptations that are required for successful applications of task-based fMRI in children, especially in the motor and language systems. The more recently introduced method of resting state fMRI is reviewed and its relative advantages and disadvantages discussed. Common pitfalls and other systems and networks that may be of interest in special circumstances also are reviewed.

Keywords: BOLD; Presurgical planning; Resting state fMRI; Task fMRI.

Publication types

Review

MeSH terms

Adult
Brain / diagnostic imaging
Brain Mapping
Brain Neoplasms*
Child
Humans
Language
Magnetic Resonance Imaging*