Understanding how Victoria, Australia gained control of its second COVID-19 wave

Nat Commun. 2021 Nov 1;12(1):6266. doi: 10.1038/s41467-021-26558-4.

Abstract

During 2020, Victoria was the Australian state hardest hit by COVID-19, but was successful in controlling its second wave through aggressive policy interventions. We calibrated a detailed compartmental model of Victoria's second wave to multiple geographically-structured epidemic time-series indicators. We achieved a good fit overall and for individual health services through a combination of time-varying processes, including case detection, population mobility, school closures, physical distancing and face covering usage. Estimates of the risk of death in those aged ≥75 and of hospitalisation were higher than international estimates, reflecting concentration of cases in high-risk settings. We estimated significant effects for each of the calibrated time-varying processes, with estimates for the individual-level effect of physical distancing of 37.4% (95%CrI 7.2-56.4%) and of face coverings of 45.9% (95%CrI 32.9-55.6%). That the multi-faceted interventions led to the dramatic reversal in the epidemic trajectory is supported by our results, with face coverings likely particularly important.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • COVID-19 / epidemiology*
  • COVID-19 / prevention & control*
  • COVID-19 / transmission
  • Epidemics*
  • Hospitalization
  • Humans
  • Middle Aged
  • Models, Theoretical
  • Physical Distancing
  • SARS-CoV-2
  • Schools
  • Victoria
  • Young Adult