Induced intragenic recombination in yeast can occur during the G1 mitotic phase

Nature. 1978 Apr 27;272(5656):795-8. doi: 10.1038/272795a0.


The conditional cell division cycle yeast mutants cdc have been used to demonstrate that intragenic recombination induced by ultraviolet or gamma rays occurs in diploids arrested in G1, a short time after irradiation and before the initiation of the S phase. This implies that pairing of homologous chromosomes does not require duplicated chromatids.

MeSH terms

  • Cell Cycle*
  • DNA Replication
  • Gamma Rays
  • Mitosis*
  • Mutation
  • Recombination, Genetic* / radiation effects
  • Saccharomyces cerevisiae / genetics*
  • Ultraviolet Rays