Survival Response of Patients With Gastric Cancer Treated With Regional Arterial-Perfusion Chemotherapy Is Correlated With Borrmann Classification

Anticancer Res. 2021 Nov;41(11):5507-5515. doi: 10.21873/anticanres.15364.

Abstract

Background/aim: The aim of the present study was to correlate the survival response to regional arterial-perfusion chemotherapy (RAPC) with Borrmann classification in patients with gastric cancer.

Patients and methods: The survival response of 270 patients with advanced gastric cancer treated with RAPC was analyzed and Borrmann classification of the tumors was retrospectively correlated to survival.

Results: The median survival time of RAPC-treated patients with Borrmann type I/II was 53 months compared with 19 and 12 months for those with Borrmann type III and IV, respectively (p<0.001).

Conclusion: Borrmann classification is a potential indicator to predict prognosis of patients with advanced gastric cancer treated with RAPC.

Keywords: Borrmann classification; Gastric cancer; arterial perfusion; overall survival; response.

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Chemotherapy, Adjuvant
  • Chemotherapy, Cancer, Regional Perfusion* / adverse effects
  • Chemotherapy, Cancer, Regional Perfusion* / mortality
  • Female
  • Gastrectomy
  • Humans
  • Lymph Node Excision
  • Male
  • Margins of Excision
  • Middle Aged
  • Neoadjuvant Therapy* / adverse effects
  • Neoadjuvant Therapy* / mortality
  • Neoplasm Staging
  • Retrospective Studies
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / mortality
  • Stomach Neoplasms / pathology
  • Time Factors
  • Treatment Outcome