Sepsis

Michael H Ackerman; Thomas Ahrens; Justin Kelly; Anne Pontillo

doi:10.1016/j.cnc.2021.08.003

Sepsis

Crit Care Nurs Clin North Am. 2021 Dec;33(4):407-418. doi: 10.1016/j.cnc.2021.08.003. Epub 2021 Oct 9.

Authors

Michael H Ackerman¹, Thomas Ahrens², Justin Kelly³, Anne Pontillo⁴

Affiliations

¹ Masters in Healthcare Innovation Program, The Ohio State University, Columbus, OH, USA. Electronic address: ackerman.249@osu.edu.
² Viven Health, 006 Woodbridge Creek Court, St Louis, MO 63129, USA.
³ OSU Wexner Medical Center - The James, 460 West 10th Avenue, Room C1138, Columbus, OH, 43210, USA.
⁴ Nursing Education Department, James Cancer Hospital Solove Research Institute, 660 Ackerman Road, 5th Floor/Room 574, Columbus, OH 43202, USA.

PMID: 34742497
DOI: 10.1016/j.cnc.2021.08.003

Abstract

This article provides an overview of the history of the sepsis definitions as well as an overview of the current understanding of the pathogenesis of sepsis. The evolution of the treatment bundles is also presented.

Keywords: Apoptosis; Bundles; SIRS; Sepsis; Surviving sepsis; qSOFA.

Publication types

Review

MeSH terms

Humans
Organ Dysfunction Scores*
Prognosis
Sepsis* / diagnosis
Sepsis* / therapy