Discussion of "Exponential-family Embedding with Application to Cell Developmental Trajectories for Single-cell RNA-seq Data"

J Am Stat Assoc. 2021;116(534):471-474. doi: 10.1080/01621459.2021.1880920. Epub 2021 Jun 8.

Abstract

Exponential-family singular value decomposition (eSVD) is a new approach for embedding multivariate data into a lower-dimensional space. It provides an elegant dimension reduction framework with flexibility to handle one-parameter exponential family distributions and proven consistency. This approach adds a valuable new tool to the toolbox of data analysts. Here we discuss a number of open problems and challenges that remain to be addressed in the future in order to unleash the full potential of eSVD and other similar approaches.

Keywords: Big Data; Dimension Reduction; Genomics; Multivariate Analysis.

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