Weaning from the Ventilator in Bronchopulmonary Dysplasia

Clin Perinatol. 2021 Dec;48(4):895-906. doi: 10.1016/j.clp.2021.08.005.

Abstract

For the newborns needing respiratory support at 36 weeks postmenstrual age, regardless of the type of ventilation used, it is critical to take into account the mechanics properties of both airways and lungs affected by severe bronchopulmonary dysplasia (sBPD). Ventilator strategies, settings, and weaning must change dramatically after sBPD is established, but to date there is almost no high-quality evidence base supporting a specific approach to guide the optimal ventilator management and weaning in patients with sBPD. Weaning from invasive mechanical ventilation, management of the immediately postextubation period, and weaning from noninvasive ventilation in patients with sBPD are the topics covered in this chapter.

Keywords: Bronchopulmonary dysplasia; Chronic ventilation; Mechanical ventilation weaning; Noninvasive ventilation weaning; Prematurity; Tracheostomy.

Publication types

  • Review

MeSH terms

  • Bronchopulmonary Dysplasia* / therapy
  • Humans
  • Infant, Newborn
  • Noninvasive Ventilation*
  • Respiration, Artificial
  • Ventilator Weaning
  • Ventilators, Mechanical