GATA2 promotes human vascular smooth muscle cell proliferation via mitofusin2-mediated Ras/Raf/MEK/ERK signaling pathway

Int J Cardiol. 2022 Jan 1:346:62-70. doi: 10.1016/j.ijcard.2021.11.012. Epub 2021 Nov 11.

Authors

Zuoguang Wang¹, Hao Wang², Qiong Wu², Yanyu Chen², Jielin Liu², Ya Liu², Dongdong Sun², Wenli Chen³

Affiliations

¹ Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China. Electronic address: wzg70@hotmail.com.
² Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing, China.
³ Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

PMID: 34774887
DOI: 10.1016/j.ijcard.2021.11.012

No abstract available

MeSH terms

Cell Proliferation
Extracellular Signal-Regulated MAP Kinases / metabolism
GATA2 Transcription Factor
Humans
MAP Kinase Signaling System*
Mitogen-Activated Protein Kinase Kinases / metabolism
Muscle, Smooth, Vascular* / metabolism
Signal Transduction
raf Kinases / metabolism

Substances

GATA2 Transcription Factor
GATA2 protein, human
raf Kinases
Extracellular Signal-Regulated MAP Kinases
Mitogen-Activated Protein Kinase Kinases