Disparities in the Management of Peritoneal Surface Malignancies

Surg Oncol Clin N Am. 2022 Jan;31(1):29-41. doi: 10.1016/j.soc.2021.07.005. Epub 2021 Oct 19.


Peritoneal surface malignancies are a group of aggressive cancers involving the peritoneum. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy can improve outcomes and survival in select patients. Despite significant advancements in care, racial disparities in peritoneal malignancy outcomes persist and may have even worsened over time. Poor adherence to guideline-recommended therapy introduces wide variability in patient care and often results in fewer options and suboptimal treatment of vulnerable populations. This review explores biological, sociodemographic, and environmental factors that contribute to disparities in peritoneal malignancy outcomes.

Keywords: Appendiceal cancer; Carcinomatosis; Colorectal cancer; Cytoreductive surgery; Disparities; Ovarian cancer; Peritoneal malignancy; Peritoneal metastases.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Colorectal Neoplasms* / pathology
  • Combined Modality Therapy
  • Humans
  • Hyperthermia, Induced* / methods
  • Peritoneal Neoplasms* / drug therapy
  • Retrospective Studies