Partnering a Compensatory Application with Activity-Aware Prompting to Improve Use in Individuals with Amnestic Mild Cognitive Impairment: A Randomized Controlled Pilot Clinical Trial

J Alzheimers Dis. 2022;85(1):73-90. doi: 10.3233/JAD-215022.


Background: Compensatory aids can help mitigate the impact of progressive cognitive impairment on daily living.

Objective: We evaluate whether the learning and sustained use of an Electronic Memory and Management Aid (EMMA) application can be augmented through a partnership with real-time, activity-aware transition-based prompting delivered by a smart home.

Methods: Thirty-two adults who met criteria for amnestic mild cognitive impairment (aMCI) were randomized to learn to use the EMMA app on its own (N = 17) or when partnered with smart home prompting (N = 15). The four-week, five-session manualized EMMA training was conducted individually in participant homes by trained clinicians. Monthly questionnaires were completed by phone with trained personnel blind to study hypotheses. EMMA data metrics were collected continuously for four months. For the partnered condition, activity-aware prompting was on during training and post-training months 1 and 3, and off during post-training month 2.

Results: The analyzed aMCI sample included 15 EMMA-only and 14 partnered. Compared to the EMMA-only condition, by week four of training, participants in the partnered condition were engaging with EMMA more times daily and using more basic and advanced features. These advantages were maintained throughout the post-training phase with less loss of EMMA app use over time. There was little differential impact of the intervention on self-report primary (everyday functioning, quality of life) and secondary (coping, satisfaction with life) outcomes.

Conclusion: Activity-aware prompting technology enhanced acquisition, habit formation and long-term use of a digital device by individuals with aMCI. ( NCT03453554).

Keywords: Alzheimer’s disease; assistive technology; dementia; functional status; memory training; quality of life; real-time systems; reminder system; smart health aids; supervised machine learning.

Publication types

  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Activities of Daily Living
  • Aged
  • Cognitive Dysfunction / rehabilitation*
  • Female
  • Humans
  • Independent Living
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Pilot Projects
  • Quality of Life*
  • Reminder Systems*
  • Self Efficacy
  • Supervised Machine Learning*
  • Surveys and Questionnaires
  • Technology Assessment, Biomedical

Associated data