Human amniotic membrane for failed macular hole. A case of initial unsuccessful outcome that resolved after amniotic membrane exchange

Tomaso Caporossi; Lorenzo Governatori; Tommaso Verdina; Stanislao Rizzo

doi:10.1177/11206721211058996

Human amniotic membrane for failed macular hole. A case of initial unsuccessful outcome that resolved after amniotic membrane exchange

Eur J Ophthalmol. 2021 Nov 15:11206721211058996. doi: 10.1177/11206721211058996. Online ahead of print.

Authors

Tomaso Caporossi¹, Lorenzo Governatori², Tommaso Verdina³, Stanislao Rizzo¹

Affiliations

¹ Department of Ophthalmology, 96983Catholic University of Sacred-Heart Foundation "Policlinico Universitario A. Gemelli" IRCCS, Rome, Italy.
² Department of Neurofarba, Ophthalmology, 9300University of Florence, Florence, Italy.
³ Institute of Ophthalmology, 9306University of Modena and Reggio Emilia, Modena, Italy.

PMID: 34779681
DOI: 10.1177/11206721211058996

Abstract

Introduction: We described a case of initial unsuccessful outcome of failed macular hole treated with amniotic membrane, that resolved after amniotic membrane exchange and silicone oil injection.

Case description: a woman affected by a high myopic macular hole that had failed to close after multiple surgeries, had been treated using an amniotic membrane graft and 20% sulfur hexafluoride but, after the gas reabsorption, the macular hole was still open, and the amnioticmembrane. A second surgery with a second amniotic membrane patch and silicone oil was carried out. Two weeks after the procedure the macular hole closed, and the final visual acuity improved from 20/400 to 20/100.

Conclusions: In this case, a second surgery, using a new amniotic membrane graft and a longer-lasting endotamponade, closed the hole and improved the visual acuity.

Keywords: Pars plana vitrectomy < vitreous / endophthalmitis; macular hole < retina; pathologic myopia < retina; retinal cell biology < retina; retinal pathology / research < retina.