AIE materials for cancer cell detection, bioimaging and theranostics

Sudesna Chakravarty; Sayan Roy Chowdhury; Sudip Mukherjee

doi:10.1016/bs.pmbts.2021.07.032

AIE materials for cancer cell detection, bioimaging and theranostics

Prog Mol Biol Transl Sci. 2021:185:19-44. doi: 10.1016/bs.pmbts.2021.07.032. Epub 2021 Aug 27.

Authors

Sudesna Chakravarty¹, Sayan Roy Chowdhury², Sudip Mukherjee³

Affiliations

¹ Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, United States.
² Department of Chemistry, Virginia Commonwealth University, Richmond, VA, United States.
³ Department of Bioengineering, Rice University, Houston, TX, United States. Electronic address: sudip.mukherjee@rice.edu.

PMID: 34782105
DOI: 10.1016/bs.pmbts.2021.07.032

Abstract

AIE materials exhibit weakly emissive or non-emissive properties in dilute solutions while emit powerful fluorescence in the aggregated/solid state. Recently, AIE based materials have gained immense attention due to their multifunctional role in cancer cell detection, bioimaging and cancer theranostics. In this present book chapter, we will highlight recent advancements of AIE materials for different cancer theranostics applications.

Keywords: AIE materials; Anti-cancer; Bioimaging; Cancer; Theranostics.

MeSH terms

Fluorescence
Humans
Neoplasms* / diagnostic imaging
Neoplasms* / therapy
Precision Medicine*