[MGMT and temozolomide sensibility]

Bull Cancer. 2021 Dec;108(12):1075-1076. doi: 10.1016/j.bulcan.2021.08.011. Epub 2021 Nov 12.
[Article in French]
No abstract available

Keywords: Glioblastome; MGMT; Methylation; Temozolomide.

Publication types

  • News

MeSH terms

  • Aged
  • Antineoplastic Agents, Alkylating / therapeutic use*
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / enzymology
  • Brain Neoplasms / radiotherapy
  • Chemoradiotherapy / methods
  • DNA Methylation
  • DNA Modification Methylases / metabolism
  • DNA Repair Enzymes / metabolism
  • Frail Elderly
  • Glioblastoma / drug therapy*
  • Glioblastoma / enzymology
  • Glioblastoma / radiotherapy
  • Humans
  • Promoter Regions, Genetic
  • Temozolomide / therapeutic use*
  • Transcription, Genetic
  • Tumor Suppressor Proteins / metabolism

Substances

  • Antineoplastic Agents, Alkylating
  • Tumor Suppressor Proteins
  • DNA Modification Methylases
  • MGMT protein, human
  • DNA Repair Enzymes
  • Temozolomide