Clinical Presentation, Imaging Features, and Management of Müller-Weiss Disease

Cureus. 2021 Oct 11;13(10):e18659. doi: 10.7759/cureus.18659. eCollection 2021 Oct.


Müller-Weiss disease (MWD) is a rare condition of unclear pathogenesis that causes navicular bone collapse and fragmentation. MWD can be challenging to diagnose and presents with midfoot and hindfoot pain and deformities. Although its incidence is unknown, MWD more commonly affects women aged between 40 and 60 years. This study reviews and summarizes the published literature on MWD to allow a better understanding of the pathomechanics, presentation, imaging modalities, and treatment options for MWD.

Keywords: midfoot pain; müller–weiss disease; navicular bone deformity; navicular bone fragmentation; paradoxical pes planus varus deformity.

Publication types

  • Review