Pneumocystis jirovecii pneumonia in a X-linked chronic granulomatous disease female carrier

IDCases. 2021 Oct 27;26:e01323. doi: 10.1016/j.idcr.2021.e01323. eCollection 2021.


The X-chromosome linked (XL) female carriers of chronic granulomatous disease (CGD) are considered to have no risk for infection. Herein we present a female CGD XL-carrier who developed Pneumocystis jirovecii pneumonia and Serratia marcescens infection associated with age-related skewing of X-chromosome inactivation.

Keywords: Chronic Granulomatous Disease; Neutrophils’ oxidative activity; Pneumocystis jirovecii; X-chromosome inactivation; X-linked carrier.

Publication types

  • Case Reports