This paper proposes a cutting head optimization method based on meshing the spatial position of the picks. According to the expanded shape of the spatial mesh composed of four adjacent picks on the plane, a standard mesh shape analysis method can be established with mesh skewness, mesh symmetry, and mesh area ratio as the indicators. The traversal algorithm is used to calculate the theoretical meshing rate, pick rotation coefficient, and the variation of cutting load for the longitudinal cutting head with 2, 3, and 4 helices. The results show that the 3-helix longitudinal cutting head has better performance. By using the traversal result with maximum theoretical meshing rate as the design parameter, the longitudinal cutting head CH51 with 51 picks was designed and analyzed. The prediction model of pick consumption is established based on cutting speed, direct rock cutting volume of each pick, pick rotation coefficient, uniaxial compressive strength, and CERCHAR abrasivity index. And the rock with normal distribution characteristics of Uniaxial Compressive Strength is used for the specific energy calculating. The artificial rock wall cutting test results show that the reduction in height loss suppresses the increase in pick equivalent loss caused by the increase in mass loss, and the pick consumption in this test is only 0.037-0.054 picks/m3. In addition, the correlation between the actual pick consumption and the prediction model, and the correlation between the actual cutting specific energy and the theoretical calculation value are also analyzed. The research results show that the pick arrangement design method based on meshing pick tip spatial position can effectively reduce pick consumption and improve the rock cutting performance.