Intestinal Spirochaetosis-A case series from the developing world

Trop Doct. 2022 Jan;52(1):134-138. doi: 10.1177/00494755211049031. Epub 2021 Nov 18.

Abstract

Spirochaetes comprise a heterogenous group of gram negative, motile, spiral shaped bacteria. Some of these pathogens are known to cause numerous human diseases such as Lyme disease, relapsing fever, syphilis and leptospirosis. However, intestinal spirochetosis is a rare condition. Patients frequently present with long-term complaints of loose stools, abdominal pain and weight loss and rectal bleeding. Hence to establish a diagnosis an endoscopy with biopsy is required. In this article, we describe four such cases, having different ages and socio- economic background, successfully treated with a short course of metronidazole.

Keywords: Intestinal spirochetosis; lower socio-economic status; metronidazole.

MeSH terms

  • Diarrhea / diagnosis
  • Diarrhea / drug therapy
  • Endoscopy
  • Humans
  • Intestines
  • Metronidazole
  • Spirochaetales Infections* / diagnosis
  • Spirochaetales Infections* / drug therapy
  • Spirochaetales Infections* / microbiology

Substances

  • Metronidazole