Psychometric validation of the Korean Patient-Reported Outcome Measurement Information System (PROMIS)-29 Profile V2.1 among patients with chronic pulmonary diseases

Danbee Kang; Jihyun Lim; Bo-Guen Kim; Heesu Nam; Youngha Kim; Eunjee Kang; Sooyeon Kim; Sungkeun Shim; Mangyeong Lee; Junghee Yoon; Hyun Lee; Sun Hye Shin; Hye Yun Park; Juhee Cho

doi:10.21037/jtd-21-591

Psychometric validation of the Korean Patient-Reported Outcome Measurement Information System (PROMIS)-29 Profile V2.1 among patients with chronic pulmonary diseases

J Thorac Dis. 2021 Oct;13(10):5752-5764. doi: 10.21037/jtd-21-591.

Authors

Danbee Kang^#^{1

2}, Jihyun Lim^#¹, Bo-Guen Kim^#³, Heesu Nam^{1

2}, Youngha Kim¹, Eunjee Kang^{1

4}, Sooyeon Kim^{1

2}, Sungkeun Shim^{1

5}, Mangyeong Lee^{1

5}, Junghee Yoon², Hyun Lee⁶, Sun Hye Shin³, Hye Yun Park³, Juhee Cho^{1

2

7}

Affiliations

¹ Center for Clinical Epidemiology, Samsung Medical Center, Seoul, Republic of Korea.
² Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.
³ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
⁴ Department of Medical Device Management and Research, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.
⁵ Department of Digital Health, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.
⁶ Division of Pulmonary, Department of Medicine, Hanyang University Hospital, Seoul, Republic of Korea.
⁷ Departments of Epidemiology and Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

^# Contributed equally.

Abstract

Background: This study aimed to validate the Korean version of the Patient-Reported Outcome Measurement Information System 29 Profile V2.1 (K-PROMIS-29 V2.1) in a sample of patients with chronic pulmonary diseases (CPDs).

Methods: Participants were recruited from the respiratory disease outpatient clinics of Samsung Medical Center in Seoul, South Korea, from September to October 2018. Participants completed a survey questionnaire, including the K-PROMIS-29 V2.1 and Short Form Health Survey version-2.0 (SF-36v2). Modified Medical Research Council (mMRC) and chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) scores were obtained these scores from electronic medical records (EMRs). Exploratory and confirmatory factor analyses (CFA) and Pearson's correlations were used to evaluate the reliability and validity of the K-PROMIS-29 V2.1.

Results: The mean age [standard deviation (SD)] was 62.8 (12.0) years, and 19.2% had less than middle-school education. Disease types included bronchiectasis (n=46, 24.5%), COPD (n=45, 23.9%), nontuberculous mycobacterial lung disease (n=25, 13.3%), interstitial lung disease (n=22, 11.7%), and others (n=50, 26.6%). Cronbach's alpha coefficients of the 7 subdomains in the K-PROMIS-29 V2.1 ranged from 0.77 to 0.96, indicating satisfactory internal consistency. In CFA, the goodness-of-fit indices were high (comparative fit index =0.90, standardised root mean residual =0.06). Moderate correlations were observed between comparable subscales of the K-PROMIS-29 V2.1 and those of the SF-36v2 (r=0.55-0.70) and CAT (r=-0.80 to 0.70).

Conclusions: The findings of this study suggest that the K-PROMIS-29 V2.1 is a reliable and valid measure for assessing a broad range of health-related quality-of-life domains in patients with CPDs.

Keywords: Patient-Reported Outcome Measurement Information System 29 Profile V2.1 (K-PROMIS-29 V2.1); Validation; chronic pulmonary diseases (CPDs); patient reported outcome.