Endoscopic Ultrasound for the Diagnosis and Staging of Biliary Malignancy

Martin Coronel; Jeffrey H Lee; Emmanuel Coronel

doi:10.1016/j.cld.2021.08.010

Endoscopic Ultrasound for the Diagnosis and Staging of Biliary Malignancy

Clin Liver Dis. 2022 Feb;26(1):115-125. doi: 10.1016/j.cld.2021.08.010. Epub 2021 Oct 25.

Authors

Martin Coronel¹, Jeffrey H Lee¹, Emmanuel Coronel²

Affiliations

¹ Department of Gastroenterology, Hepatology, and Nutrition, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1466, Houston, TX 77030, USA.
² Department of Gastroenterology, Hepatology, and Nutrition, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1466, Houston, TX 77030, USA. Electronic address: ecoronel@mdanderson.org.

PMID: 34802657
DOI: 10.1016/j.cld.2021.08.010

Abstract

Cholangiocarcinoma (CCA) is the most common neoplasm of the biliary tract. The biological behavior and prognosis of CCA vary depending on the tumor's location in the biliary tree, dictating a different diagnostic, and treatment approach. Establishing a diagnosis of CCA remains a challenge and up to 20% of biliary strictures can yield indeterminate results, despite extensive evaluation. Endoscopic ultrasound (EUS) has become an effective diagnostic tool, as it provides high-quality images of the bile duct and allows for the sampling of strictures in the same plane of view. In this chapter, we explore the utility of EUS as a diagnostic and staging tool for biliary cancers.

Keywords: Biliary strictures; Cholangiocarcinoma; Endoscopic ultrasound; Fine-needle aspiration.

Publication types

Review

MeSH terms

Bile Duct Neoplasms* / diagnostic imaging
Bile Ducts, Intrahepatic / diagnostic imaging
Cholangiocarcinoma* / diagnostic imaging
Cholangiopancreatography, Endoscopic Retrograde
Endosonography
Humans
Sensitivity and Specificity