[Myocardial infarction in the young : clinical characteristics, therapeutic aspects and in-hospital complications]

Ann Cardiol Angeiol (Paris). 2022 Apr;71(2):90-94. doi: 10.1016/j.ancard.2021.10.019. Epub 2021 Nov 19.
[Article in French]

Abstract

Aim of the study: The aim of our study was to assess the clinical, electrical, angiographic and therapeutic characteristics of young patients with acute myocardial infarction and to describe the prevalence of in-hospital complications.

Patients and methods: FromJanuary 2014 to May 2017, we retrospectively studied data of patients with acute myocardial infarction younger than 45 years old in the department of cardiology of Charles Nicolle hospital of Tunis.

Results: We enrolled 108 patients in the study. The prevalence of myocardial infarction in young patients was 8.5%. The mean age was 39.5 ± 5.5 years with a sex-ratio of 11. The most frequent cardiovascular risk factors were smoking (88%) and dyslipidaemia (51.9%). We reported 75 cases of ST segment elevation myocardial infarction. Primary angioplasty was performed in 41.3% of cases while lytic therapy was administered for the rest of the patients. It was successful in 75% of cases. Among 33 patients who presented with non-ST segment elevation myocardial infarction, percutaneous coronary angioplasty was performed in 60.6% of patients while 15.2% have undergone coronary artery bypass surgery and 24.2% received medical treatment only. In-hospital complications occurred in 39.8% of cases. In-hospital mortality was 1.9 %.

Conclusions: Acute myocardial infarction in the young represents a serious health problem. Primary preventive measures aimed at preventing our youth from adopting tobacco use and developing dyslipidemia should be implemented to delay and even to avoid the onset of coronary artery disease.

Keywords: Coronarographie; Coronary angiography; Facteur de risque; Infarctus myocarde; Myocardial infarction; Prognosis; Pronostic; Risk factor.

MeSH terms

  • Adolescent
  • Adult
  • Angioplasty, Balloon, Coronary*
  • Hospitals
  • Humans
  • Middle Aged
  • Myocardial Infarction* / epidemiology
  • Myocardial Infarction* / etiology
  • Myocardial Infarction* / therapy
  • Non-ST Elevated Myocardial Infarction*
  • Retrospective Studies
  • Risk Factors
  • ST Elevation Myocardial Infarction* / epidemiology
  • ST Elevation Myocardial Infarction* / etiology
  • ST Elevation Myocardial Infarction* / therapy
  • Treatment Outcome