Lower Eyelid Ectropion Secondary to Over-the-Counter Treatment of Xanthelasma

Ophthalmic Plast Reconstr Surg. 2022 Jan-Feb;38(1):e25-e28. doi: 10.1097/IOP.0000000000002070.


Xanthelasmas are localized accumulations of lipids, mainly cholesterol, that can occur in the epidermis, dermis, and muscle of the eyelids. They are the most common cutaneous presentation of xanthoma and occur most commonly on the upper eyelid near the inner canthus. Despite their benign presence, xanthelasmas can be cosmetically concerning. With this in mind, several treatment modalities have been described to eliminate the appearance. We report the first case to describe a cicatricial ectropion from the topical treatment, "Glycolic acid, Lactic acid, Mandelic acid, Salicylic acid, Resorcinol, Jessners peel" (XanthelR, 483 Green Lanes, London, N13 4BS).

MeSH terms

  • Ectropion* / surgery
  • Eyelids / surgery
  • Humans
  • Skin
  • Skin Transplantation
  • Xanthomatosis* / diagnosis