Current trends in anesthetic depth and antinociception monitoring: an international survey

J Clin Monit Comput. 2022 Oct;36(5):1407-1422. doi: 10.1007/s10877-021-00781-2. Epub 2021 Nov 26.

Abstract

Current trends in anesthetic depth (i.e., hypnosis) and antinociception monitoring are unclear. We thus aimed to determine contemporary perspectives on monitoring these components of anesthesia during general anesthesia. Participants received and responded anonymously to an internet-based international survey supported by the European Society of Anaesthesiology and Intensive Care. Comparisons, when applicable, were carried out using Chi2 analysis or Fischer's exact test. A total of 564 respondents, predominantly from Europe (80.1%), participated. There was a strong participation from Belgium (11.5%). A majority (70.9%) of anesthetists considered hypnotic monitoring important on most occasions to always. In contrast, a majority (62.6%) never or only occasionally considered antinociception monitoring important. This difference in the perceived importance of anesthetic depth versus antinociception monitoring was significant (p < 0.0001). A majority of respondents (70.1%) believed that guiding hypnosis and antinociception using these monitors would improve patient care on most occasions to always. Nonetheless, a substantial number of participants were unsure if hypnotic (23%) or antinociception (32%) monitoring were recommended and there was a lack of knowledge (58%) of any published algorithms to titrate hypnotic and/or antinociceptive drugs based on the information provided by the monitors. In conclusion, current trends in European academic centers prioritize anesthesia depth over antinociception monitoring. Despite an agreement among respondents that applying strategies that optimize anesthetic depth and antinociception could improve outcome, there remains a lack of knowledge of appropriate algorithms. Future studies and recommendations should focus on clarifying goal-directed anesthetic strategies and determine their impact on perioperative patient outcome.

Keywords: Burst suppression; General anesthesia; Goal-directed therapy; Intraoperative monitoring; Pain.

MeSH terms

  • Analgesics / therapeutic use
  • Anesthesia, General
  • Anesthetics*
  • Electroencephalography
  • Humans
  • Hypnotics and Sedatives
  • Monitoring, Intraoperative*
  • Surveys and Questionnaires

Substances

  • Analgesics
  • Anesthetics
  • Hypnotics and Sedatives