Is there a role for lung-protective ventilation in healthy children?

Paediatr Anaesth. 2022 Feb;32(2):278-285. doi: 10.1111/pan.14345. Epub 2021 Dec 5.


Lung-protective ventilation (LPV) has been adopted in the theater environment as a strategy to reduce pulmonary complications under anesthesia. Postoperative pulmonary complications are not infrequent and may have significant implications on the postoperative length of stay as well as the morbidity and mortality of pediatric patients. There is evidence in the adult literature to suggest that intraoperative LPV strategies may reduce the risk of such complications. The utility of LPV strategies in healthy children is not well researched, and the data from critical care studies appear to be conflicting. To ascertain the value of intraoperative LPV in pediatric patients, it is important to understand the pathophysiology of pediatric ventilator-induced lung injury and the basis of LPV strategies. The current evidence in adult and pediatric populations, including pediatric intensive care, is reviewed to gain insight into the role and value of intraoperative LPV for pediatric patients.

Keywords: lung-protective ventilation; pediatric patients.

Publication types

  • Review

MeSH terms

  • Adult
  • Child
  • Humans
  • Lung
  • Positive-Pressure Respiration*
  • Postoperative Complications / prevention & control
  • Respiration, Artificial
  • Tidal Volume
  • Ventilator-Induced Lung Injury* / prevention & control