Rapid spontaneous resolution of corneal hydrops in post-CXL keratitis

BMJ Case Rep. 2021 Nov 30;14(11):e246141. doi: 10.1136/bcr-2021-246141.

Abstract

An 11-year-old boy presented with right eye post-Corneal Collagen Cross-Linking (CXL) keratitis, which was complicated by acute corneal hydrops (CH). Keratitis was managed by topical antibiotics, and CH was managed conservatively. Cornea was monitored with serial anterior segment optical coherence tomography (ASOCT) scans. Spontaneous resolution of CH usually takes 8-12 weeks, but in this case it completely resolved in 3 weeks. Rapid resolution of CH after post-CXL keratitis could be attributed to a thinner cornea, increased interlamellar cohesive strength between collagen fibrils of corneal stroma coupled with normal functioning endothelial pump.

Keywords: anterior chamber; visual pathway.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Collagen
  • Cornea
  • Corneal Stroma
  • Cross-Linking Reagents
  • Humans
  • Keratitis* / drug therapy
  • Keratoconus*
  • Male
  • Photosensitizing Agents
  • Riboflavin
  • Ultraviolet Rays

Substances

  • Cross-Linking Reagents
  • Photosensitizing Agents
  • Collagen
  • Riboflavin