Evaluation of hematological parameters related to systemic inflammation in acute and subacute/chronic low back pain

Biomark Med. 2022 Jan;16(1):31-40. doi: 10.2217/bmm-2021-0431. Epub 2021 Dec 3.

Abstract

Aim: To compare the hematological parameters associated with systemic inflammation between acute and subacute/chronic nonspecific low back pain and to evaluate their diagnostic roles in relation to chronicity in low back pain. Materials & methods: This retrospective case-control study included 150 participants aged 18-65 years with acute nonspecific low back pain, 150 with subacute/chronic nonspecific low back pain, 150 as the control group. Results: Red cell distribution width was significantly higher in the subacute/chronic pain group compared with the acute pain group (p = 0.003), and had a poor diagnostic value for chronicity (cutoff: 11.95, p = 0.003). There were no significant differences in terms of other parameters (p > 0.05). Conclusion: Red cell distribution width has a poor diagnostic value for chronicity in nonspecific low back pain.

Keywords: blood cell count; chronic pain; inflammation; low back pain.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Animals
  • Chronic Pain
  • Female
  • Hematologic Tests
  • Humans
  • Inflammation / blood*
  • Low Back Pain / blood*
  • Low Back Pain / complications
  • Mice
  • Middle Aged
  • Young Adult