Dynamical self-organization and efficient representation of space by grid cells

Abstract

To plan trajectories and navigate, animals must maintain a mental representation of the environment and their own position within it. This "cognitive map" is thought to be supported in part by the entorhinal cortex, where grid cells are active when an animal occupies the vertices of a scaling hierarchy of periodic lattices of locations in an enclosure. Here, we review computational developments which suggest that the grid cell network is: (a) efficient, providing required spatial resolution with a minimum number of neurons, (b) self-organizing, dynamically coordinating the structure and scale of the responses, and (c) adaptive, re-organizing in response to changes in landmarks and the structure of the boundaries of spaces. We consider these ideas in light of recent discoveries of similar structures in the mental representation of abstract spaces of shapes and smells, and in other brain areas, and highlight promising directions for future research.