Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model

Nat Methods. 2021 Dec;18(12):1427-1440. doi: 10.1038/s41592-021-01327-9.


Rigorous record-keeping and quality control are required to ensure the quality, reproducibility and value of imaging data. The 4DN Initiative and BINA here propose light Microscopy Metadata specifications that extend the OME data model, scale with experimental intent and complexity, and make it possible for scientists to create comprehensive records of imaging experiments.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Biomedical Research / organization & administration
  • Calibration
  • Data Collection
  • Data Mining / standards
  • Humans
  • Metadata*
  • Microscopy / instrumentation*
  • Microscopy / methods*
  • Microscopy / standards*
  • Quality Control
  • Reproducibility of Results
  • Societies, Scientific
  • Software
  • Systems Integration
  • User-Computer Interface