Interlobular Septal Thickening in a Young Man With Dyspnea

Chest. 2021 Dec;160(6):e645-e650. doi: 10.1016/j.chest.2021.07.2163.

Abstract

A 30-year-old man with a history of childhood asthma, a 15-pack-year smoking history, and methamphetamine abuse was intubated and started on mechanical ventilation because of acute hypoxic respiratory failure after experiencing progressive dyspnea and a nonproductive cough over the previous year. During the previous 3 months, he had multiple clinic visits, with chest radiographs showing diffuse, bilateral, reticulonodular opacities and small bilateral pleural effusions and was treated for community-acquired pneumonia. Testing for COVID pneumonia was negative, and he failed to respond to antimicrobial therapy. Physical examination on admission showed diffuse fine crackles bilaterally on lung auscultation. Admission laboratory test results were unremarkable.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / pathology
  • Adrenal Gland Neoplasms / secondary
  • Adult
  • Biomarkers, Tumor / analysis
  • Carcinoma / diagnosis*
  • Carcinoma / pathology
  • Diagnosis, Differential
  • Dyspnea
  • Fatal Outcome
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / pathology
  • Lymphangitis / diagnosis*
  • Lymphangitis / pathology
  • Lymphatic Metastasis
  • Male
  • Neoplasm Invasiveness
  • Tomography, X-Ray Computed

Substances

  • Biomarkers, Tumor