Research-Relevant Clinical Pathology Resources: Emphasis on Mice, Rats, Rabbits, Dogs, Minipigs, and Non-Human Primates

ILAR J. 2021 Dec 31;62(1-2):203-222. doi: 10.1093/ilar/ilab028.


Clinical pathology testing for investigative or biomedical research and for preclinical toxicity and safety assessment in laboratory animals is a distinct specialty requiring an understanding of species specific and other influential variables on results and interpretation. This review of clinical pathology principles and testing recommendations in laboratory animal species aims to provide a useful resource for researchers, veterinary specialists, toxicologists, and clinical or anatomic pathologists.

Keywords: Clinical chemistry; clinical pathology; coagulation; cytology; hematology; laboratory animal; safety assessment; toxicology.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Laboratory
  • Biomedical Research*
  • Dogs
  • Mice
  • Pathology, Clinical*
  • Primates
  • Rabbits
  • Rats
  • Swine
  • Swine, Miniature