Abstract
LY 164846, a new oral cephalosporin, demonstrated very good inhibitory and bactericidal activities against Haemophilus influenzae irrespective of the production of beta-lactamase by the test strains. However, its activity was not markedly superior to that of either Augmentin (amoxicillin plus clavulanate) or cefaclor.
Publication types
-
Comparative Study
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / pharmacology*
-
Cephalosporins / pharmacology*
-
Drug Resistance, Microbial
-
Haemophilus influenzae / drug effects*
-
Haemophilus influenzae / enzymology
-
beta-Lactamases / metabolism
Substances
-
Anti-Bacterial Agents
-
Cephalosporins
-
LY 164846
-
beta-Lactamases