Comparative activities of LY 164846 and other orally administered beta-lactam antibiotics against Haemophilus influenzae

Antimicrob Agents Chemother. 1986 Jun;29(6):1090-1. doi: 10.1128/AAC.29.6.1090.

Abstract

LY 164846, a new oral cephalosporin, demonstrated very good inhibitory and bactericidal activities against Haemophilus influenzae irrespective of the production of beta-lactamase by the test strains. However, its activity was not markedly superior to that of either Augmentin (amoxicillin plus clavulanate) or cefaclor.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Cephalosporins / pharmacology*
  • Drug Resistance, Microbial
  • Haemophilus influenzae / drug effects*
  • Haemophilus influenzae / enzymology
  • beta-Lactamases / metabolism

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • LY 164846
  • beta-Lactamases