Hemorrhagic complications of piperacillin therapy

J Urol. 1986 Aug;136(2):454-5. doi: 10.1016/s0022-5347(17)44906-8.


Clinically significant hemorrhage associated with extended spectrum anti-Pseudomonas penicillins is uncommon. We describe 2 patients with bleeding complications owing to piperacillin. In addition, we review the incidence and mechanism of this adverse reaction, and make suggestions for the management of these patients.

Publication types

  • Case Reports

MeSH terms

  • Blood Coagulation Tests
  • Blood Platelet Disorders / chemically induced*
  • Female
  • Gastrointestinal Hemorrhage / chemically induced*
  • Humans
  • Male
  • Middle Aged
  • Piperacillin / adverse effects*
  • Piperacillin / therapeutic use
  • Premedication


  • Piperacillin