Optic neuritis after COVID-19 vaccine application

Clin Exp Neuroimmunol. 2022 May;13(2):72-74. doi: 10.1111/cen3.12682. Epub 2021 Nov 22.


As the COVID-19 pandemic continues to rise, the development of effective vaccines is of crucial importance to prevent further morbidity and mortality. In parallel, some rare adverse events related to COVID-19 vaccines, have been reported, most of them mild. Here we report the case of a previously healthy 19-year-old woman who developed optic neuritis 1 week after single dose of Ad26.COV2.S vaccine with marked improvement after management with steroids. Although causality cannot be confirmed due to lack of a biological marker, this case may help to guide further research for potential pathogenic mechanism.

Keywords: SARS‐Cov2; adverse effects; optic neuritis; vaccination; viral vector vaccine.

Publication types

  • Case Reports