Glutathione augments the activation of cytotoxic T lymphocytes in vivo

Immunobiology. 1986 Aug;172(1-2):151-6. doi: 10.1016/s0171-2985(86)80061-4.

Abstract

The activation of cytotoxic T lymphocytes (CTL) in vivo was found to be augmented by glutathione if injected i.p. in the late phase but not in the early phase of the response. The effect of glutathione possibly resembles the augmenting effect of 2-mercaptoethanol in lymphocyte cultures.

MeSH terms

  • Animals
  • Dose-Response Relationship, Immunologic
  • Glutathione / immunology
  • Glutathione / pharmacology*
  • Mice
  • Mice, Inbred C3H
  • T-Lymphocytes, Cytotoxic / analysis
  • T-Lymphocytes, Cytotoxic / drug effects*

Substances

  • Glutathione