Memory: Neurobiological mechanisms and assessment

Ind Psychiatry J. 2021 Oct;30(Suppl 1):S311-S314. doi: 10.4103/0972-6748.328839. Epub 2021 Oct 22.

Abstract

Memory is the process of retaining of knowledge over a period for the function of affecting future actions. It can be divided into declarative and procedural types. The process of memory consolidation is done in the hippocampus. The long-term memories are spread among various areas of the cerebrum depending on the different perceptual properties. The process of long-term potentiation and molecular changes occurring during memory formation are discussed in detail below. The steps involved in memory formation include encoding, storage, and recall (retrieval) in that order. Amnesia is a phenomenon in which there is the problem in memory formation which can be due to trauma to the brain, certain diseases, or stressors. While the assessment of memory has greatly improved, we are only beginning to understand the underlying mechanisms.

Keywords: Amnesia; declarative/explicit memory; encoding; long-term potentiation; memory; neural plasticity; procedural/implicit memories; recall; retrieval; storage.